Table 1.
Descriptive echocardiographic variables.
| Variable | AVA index ≥0.6 cm2/m2 n = 659 |
AVA index <0.6 cm2/m2 n = 26 |
P-value |
|---|---|---|---|
| Males (%) | 42.0 | 42.3 | 1.0 |
| Age (years) | 75.8 (5.7) | 79.7 (4.7) | 0.0006 |
| BSA (m2) | 1.84 (0.20) | 1.84 (0.17) | 1.0 |
| LV end-diastolic diameter (cm) | 4.42 (0.65) | 4.35 (0.44) | 0.59 |
| LV end-systolic diameter (cm) | 2.96 (0.66) | 2.98 (0.44) | 0.88 |
| LV mass index (g/m2) | 89.8 (25.0) | 100.7 (20.3) | 0.029 |
| LV ejection fraction (%) | 62.4 (7.0) | 62.0 (3.8) | 0.77 |
| LVOT diameter (cm) | 2.03 (0.28) | 1.78 (0.25) | <0.0001 |
| LVOT peak velocity (cm/s) | 97.5 (19.2) | 91.4 (18.6) | 0.11 |
| LVOT velocity integral (cm) | 20.8 (5.5) | 20.9 (5.3) | 0.85 |
| Stroke volume index (ml/m2) | 36.4 (10.0) | 28.8 (9.7) | 0.0002 |
| Aortic valve calcification grade (0–3) | 0.85 (0.74) | 1.52 (0.98) | <0.0001 |
| Peak aortic valve velocity (cm/s) | 134.3 (34.3) | 263.0 (76.6) | <0.0001 |
| Aortic valve velocity integral (cm) | 28.3 (7.8) | 57.8 (20.7) | <0.0001 |
| Peak aortic valve gradient (mmHg) | 7.7 (4.5) | 29.9 (15.4) | <0.0001 |
| Mean aortic valve gradient (mmHg) | 3.5 (2.1) | 14.1 (7.7) | <0.0001 |
| Aortic valve area (cm2) | 2.43 (0.74) | 0.89 (0.16) | <0.0001 |
| AVA index (cm2/m2) | 1.32 (0.36) | 0.49 (0.09) | <0.0001 |
AVA = aortic valve area, BSA = body surface area, LV = left ventricular, LVOT = left ventricular outflow tract.