Figure 6.

ROC1 expression in human bladder cancer tissues. (A) Immunohistochemical staining of ROC1, DEPTOR and E-cadherin in human bladder cancer. Representative immunohistochemistry images of non-muscle-invasive or muscle-invasive cancer are shown. (B) Correlation of the immunostaining intensities of ROC1, DEPTOR and E-cadherin with cancer invasiveness. Immunostaining intensity was divided into two groups (high and low), and the association of intensity with cancer invasiveness (non-muscle-invasive cancer or muscle-invasive cancer) was analysed by a χ²-test for each protein. The P-value for each association is shown. Scale bar=50 μm.