TABLE 2. Shared mechanisms in the pathophysiology of major psychiatric disorders.

ARNTL1: aryl hydrocarbon receptor nuclear translocator-like protein 1, BAG 1: Bcl-2 associated gene product-1, BD: bipolar disorder, CLOCK: circadian locomotor output cycles kaput, FKBP51: FK506-binding protein51, 4-HNE: 4-hydrooxynonenol, GR: glucocorticoid receptor, IL-1Ra: interleukin 1 receptor antagonist, KAT: kynurenine aminotransferase, KMO: kynurenine mono-oxygenase, MDD: major depressive disorder, MT: melatonin receptor, NC: normal control, NMDA: N-methyl D-aspartate receptor, NPAS2: neuronal PAS domain-containing protein 2, NR1D1: nuclear receptor subfamily 1, group D, member 1, PER3: period circadian protein homolog 3, PIC: pro-inflammatory cytokines, QA: quinolinic acid, ROS: reactive oxygen species, SAD: seasonal affective disorder, SCZ: schizophrenia, sTNFR1: soluble tumor necrosis factor receptor1, vWF: von Willibrand factor.