TABLE 1 .
Group and maternal ID no. or parameter |
Infant’s last negative HIV DNA results |
Infant’s first positive HIV DNA result |
Duration of BFb (mo) |
No. of CD4 cells/mm3 |
Maternal log10 plasma VLc |
Env virus subtype |
Env cloning and plasma neutralization time point |
% Maximum pairwise distance |
---|---|---|---|---|---|---|---|---|
Nontransmitting | ||||||||
MA411 | M24 | NAd | 19.5 | 416 | 5.13 | A | P33 | 4.86 |
MB807 | M24 | NA | 14.5 | 217 | 4.78 (W6) | A | P32 | 3.30 |
MF074 | M24 | NA | 12.5 | NA | 5.01 | A | W3 | 1.12 |
MF600 | M24 | NA | 16.5 | 344 | 5.49 | C | W2 | 1.38 |
MG540 | M24 | NA | 11.5 | 285 | 5.06 | A | P32 | 2.58 |
ML156 | M9 | NA | 11.23 | 410 | 5 | A/D | P32 | 1.98 |
MM471 | M24 | NA | 22.5 | 360 | 5.26 | A | P32 | 3.20 |
MM834 | M24 | NA | 18.5 | 633 | 5.11 | D | P32 | 0.94 |
MO862 | M24 | NA | 10.5 | 134 | 4.86 | A | P33 | 5.97 |
MP199 | M24 | NA | 18.5 | 389 | 5.22 (P38) | A | W0 | 5.12 |
Transmitting | ||||||||
MB549 | W0 | W6 | 3.47 | 411 | 6.25 | A | P30 | 1.24 |
MC046 | W0 | W6 | 3 | 255 | 5.05 | A | P35 | 2.55 |
MF403 | W0 | W6 | 29.5 | 213 | 5.07 | A | W0 | 0.87 |
MF520 | W1 | W14 | 27.5 | 511 | 5.8 | A | P32 | 1.41 |
MF535 | W1 | W6 | 19.5 | 690 | 5.53 | A/D | W0 | 6.22 |
MJ412 | W0 | W6 | 22.5 | 293 | 4.98 | A/C/D | P32 | 5.88 |
MJ613 | W0 | W6 | 9.67 | 104 | 4.7 | A | P32 | 5.28 |
MK184 | W0 | W6 | 3.1 | 568 | 4.85 | D | P34 | 3.03 |
ML035 | W0 | W6 | 7.9 | 249 | 4.26 | A/D | P32 | 3.65 |
MM596 | W0 | W6 | 3.5 | 392 | 5.65 | A | W0 | 3.66 |
P value | 0.36 | 0.93 | 0.88 | 0.65 |
P values represent comparisons of nontransmitting and transmitting mother cohort characteristics by Mann-Whitney U tests. Maternal viral loads are from the same visit as envelope cloning, except where indicated in parentheses. W, week after delivery; P, week of pregnancy; M, month after delivery.
BF, breastfeeding.
VL, viral load.
NA, not applicable/available.