Table 2. Scores of fibrosis in the liver before and after the treatment with Liraglutide.
Cont | O+S | O+L | OD+S | OD+L | |
---|---|---|---|---|---|
Steatosis score | 0.00 ±0.00 | 2.75 ±0.46** | 0.88 ±0.35## | 2.75 ±0.46** | 1.88 ±0.83¤ |
Inflammation score | 0.75 ±0.46 | 2.00 ±0.76** | 1.00 ±0.76## | 2.00 ±0.76** | 1.25 ±0.46¤ |
Ballooning score | 0.00 ±0.00 | 1.13 ±0.35** | 0.25 ±0.46## | 1.13 ±0.59** | 0.38 ±0.52¤ |
NASH score | 0.25 ±0.46 | 5.88 ±0.86** | 2.13 ±0.93## | 5.88 ±0.64** | 3.50 ±0.93¤¤ |
Abbreviations: Cont, control group; NASH, nonalcoholic steatohepatitis; O+S, obese alone+saline; O+L, obese with Liraglutide treatment; OD+S, diabetobese+saline; OD+L, diabetobses with Liraglutide treatment. Data are the means±s.e. Comparative analyses were performed as: and **P<0.01 versus the negative control group; ##P<0.01 versus the O+S group; ¤P<0.05 and ¤¤P<0.01 versus the OD+S group.