FIGURE 1.

LC-ESI/MS of the crude mixture resulting from the synthesis of sMamb-1 in the absence of pseudoproline. Analysis was performed on an Agilent 1100 series (Santa Clara, CA) coupled on line to ion trap mass spectrometer Esquire equipped with an AP-ESI source (Bruker, Germany) LC separation Xbridge C18 BEH300, 3.5 μm (4.6 × 150 mm), gradient: 10–45% acetonitrile in 0.1% TFA, 45 min, 1 ml·min⁻¹. The sequence of sMamb-1 is shown at the top of the figure.