TABLE 3.

Calculated occurrence [%] of hydrogen-bonds formed between the antibiotic donor/acceptor groups (in parenthesis) and the porin residues

The latter are reported in decreasing z-coordinate order. Only the H-bonds with an occurrence ≥20% are reported. FES regions are labeled using the same numbers and asterisks as in Fig.4 a–d. The FES regions located at the porin constriction zone are shaded. Antibiotic's donor/acceptor groups are labeled as follows: “CO₂” carboxyl oxygens; “LO” β-lactam carbonyl oxygen; “NH₂⁺” imipenem's terminal amino group; “NH₂⁺” meropenem's charged amino group; “OH” side chain hydroxyl group.