FIGURE 9.

Ube2w KO skin-derived fibroblasts show no difference in response to various cell stressors. A, representative cell survival at various tunicamycin concentrations; the figure shows results for fibroblasts from four individual Ube2w KO and HET mice. B, compilation of LD₅₀ results from experiments as in A; each symbol represents a different donor mouse. C–H, compilation of LD₅₀ results for treatment with thapsigargin (C), H₂O₂ (D), methyl methanesulfonate (MMS) (E), cadmium (F), glucose deprivation (G), and NH₄Cl (H). All graphs show means ± S.E. (n = 4). *, p < 0.05. All graphs show mean ± S.E. indicated by the error bars (n = 4).