Table 2. Univariate and multivariate analysis for overall survival (Cox proportional hazards regression model).

Variable	Univariate analysis		Mutivariate analysis
	No.	pvalue	HR	95% CI	pvalue
KCTD12 expression		0.001*	0.239	0.084–0.677	0.007*
low expression	129
high expression	28
Age		0.253	1.139	0.678–1.914	0.622
≤55	53
>55	104
Gender		0.537	0.867	0.514–1.462	0.592
Male	68
Female	89
Tumor size (cm)		0.965	1.814	1.016–3.239	0.044*
≤5	113
>5	44
Clinical Stage		0.000*	2.404	0.829–6.972	0.106
I+II	50
III+IV	107
T classification		0.191	1.035	0.476–2.250	0.932
T1+T2	24
T3+T4	133
N classification		0.000*	1.442	0.897–2.318	0.131
N0	57
N1	46
N2+N3	54
M classification		0.000*	2.289	1.320–3.967	0.003*
M0	121
M1	36
HR: Hazard Ratio; CI, confidence interval; *p < 0.05

^* P < 0.05.