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. 2016 Feb 3;7:10533. doi: 10.1038/ncomms10533

Figure 10. Atg16L1 hypomorphs show developmental retention in the gut.

Figure 10

(a) Effect of decreased Atg16L1 levels on growth of gut villi length. Representative gut section from wild-type and Atg16L1 hypomorph (Atg16hyp) 10–15 weeks old mice. (b) Quantification of villi length from wild-type and Atg16L1 hypomorph (Atg16hyp) 10–15 weeks old mice. **P<0.01 by unpaired t-test. n=4. Error bars=s.e.m. (c) Hes1 immunostaining in gut from wild-type and Atg16L1 hypomorph (Atg16hyp) mice. (d) Grem1 immunostaining in gut from wild-type and Atg16L1 hypomorph (Atg16hyp) mice. (e) Quantification of Grem1-positive cells per crypt in wild-type and Atg16L1 hypomorph (Atg16hyp) mice. **P<0.01 by paired t-test. n=3. Error bars=s.e.m. Scale bar, 50 μm.