Table 3.
Database for Annotation, Visualization, and Integrated Discovery Annotation Clusters for Genes That Are Up-Regulated by TGF-β1 and Reversed by PGE2
| Annotation Cluster | Enrichment Score | Representative Annotation within Cluster | Gene Number | P Value | FDR |
|---|---|---|---|---|---|
| Cluster 1 | 6.01 | Cell Adhesion (keywords) | 36 | 3.97E-09 | 5.48E-06 |
| Cluster 2 | 5.94 | Contractile Fiber (gene ontology) | 15 | 3.86E-08 | 5.16E-05 |
| Cluster 3 | 4.96 | Actin Binding (gene ontology) | 23 | 5.77E-07 | 8.34E-04 |
| Cluster 4 | 4.15 | Signal Peptide (keywords) | 95 | 1.81E-06 | 2.93E-03 |
| Cluster 5 | 3.98 | Cytoskeletal Protein Binding (gene ontology) | 27 | 8.37E-06 | 1.21E-02 |
| Cluster 6 | 3.64 | Muscle Protein (keywords) | 9 | 1.22E-05 | 1.68E-02 |
| Cluster 7 | 3.53 | Cell Motion (gene ontology) | 26 | 9.79E-06 | 1.69E-02 |
| Cluster 8 | 3.08 | Collagen Binding (gene ontology) | 8 | 5.75E-06 | 8.31E-03 |
| Cluster 9 | 2.92 | Extracellular Matrix Structural Constituent (gene ontology) | 14 | 1.34E-08 | 1.93E-05 |
| Cluster 10 | 2.72 | Muscle Organ Development (gene ontology) | 23 | 2.29E-10 | 3.96E-07 |
Definition of abbreviations: FDR, false discovery rate; PGE2, prostaglandin E2; TGF-β1, transforming growth factor-β1.