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. 2015 Nov;53(5):625–636. doi: 10.1165/rcmb.2014-0221OC

Figure 6.

Figure 6.

STAT1 mediates IL-10 mRNA expression but suppresses Foxp3 mRNA levels in lung tissue after OVA sensitization and exposure to MWCNTs. Levels of IL-10 and Foxp3 mRNA in lung tissue from WT mice (open bars) or Stat1−/− mice (solid bars) were measure by Taqman real-time RT-PCR. (A) IL-10 mRNA levels at 1 and 21 days after exposure to MWCNT after OVA sensitization. (B) Foxp3 mRNA levels at 1 and 21 days after exposure to MWCNT after OVA sensitization. Data are the mean ± SEM (n = 3 animals for each group). *P < 0.0.05, **P < 0.01 compared with control as determined by one-way ANOVA; ##P < 0.01, ###P < 0.001 between genotypes within the same treatment group as determined by two-way ANOVA.