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. 2016 Jan 10;24(2):70–83. doi: 10.1089/ars.2015.6315

FIG. 7.

FIG. 7.

Illustrative diagram of the involved pathways. H2S attenuated inflammatory hepcidin production through two novel pathways, namely reducing IL-6 secretion via its anti-inflammatory property and promoting SIRT1-mediated STAT3 deacetylation, which in turn suppresses STAT3 and hepcidin activation.