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. 2016 Feb 4;7:10610. doi: 10.1038/ncomms10610

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(a) Panel of devices with varying diameters and depths. (b) Principal component analysis of A. nidulans grown on GMM agar in wells of varying diameter and depth and extracted with PeOH. Legend values of diameter and depth are given in microns. ‘Macroscale' refers to core samples of fungal growth on a 10-cm petri dish while ‘Media control' refers to core samples of agar alone. Each dot represents one of five independent cultures per condition from one experiment and the shaded ellipses represent 95% confidence intervals for each of the different diameters or control conditions. (c) Loadings plot of individual features for the PCA in b. Each dot represents one feature. Features in pink were putatively annotated as A. nidulans secondary metabolites based on exact mass <10 p.p.m. error (Supplementary Table 3).