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. 2016 Feb 4;7:10623. doi: 10.1038/ncomms10623

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Inline graphic — (a) Curves represent representative simultaneous recordings of cellular Ca²⁺ (black ratio curve) and (red inverted curve) signals over time of a single fura-2/am-loaded embryonic ventricular cardiomyocyte expressing G-geNOp. The cell was treated with 30 μM S-NO-HSA in the presence of extracellular Ca²⁺ using a perfusion system (n=4). (b) Representative recordings of cellular dynamics (red inverted curve, n=4) of human glioblastoma cells (U87-MG cells) expressing C-geNOp. Cells were either treated with a mixture of 10 μM PROLI NONOate and 10 μM NOC-7 (red curve) or remained untreated (control cell, black curve). (c) Cell velocity of glioblastoma cells in μm min⁻¹ extracted from the X/Y positions over time of a control cell (black columns) and a cell treated with donors as indicated in b and d. (d) Graphs represent X/Y positions of glioblastoma cells over time as indicated in b and c.

(a) Curves represent representative simultaneous recordings of cellular Ca²⁺ (black ratio curve) and (red inverted curve) signals over time of a single fura-2/am-loaded embryonic ventricular cardiomyocyte expressing G-geNOp. The cell was treated with 30 μM S-NO-HSA in the presence of extracellular Ca²⁺ using a perfusion system (n=4). (b) Representative recordings of cellular dynamics (red inverted curve, n=4) of human glioblastoma cells (U87-MG cells) expressing C-geNOp. Cells were either treated with a mixture of 10 μM PROLI NONOate and 10 μM NOC-7 (red curve) or remained untreated (control cell, black curve). (c) Cell velocity of glioblastoma cells in μm min⁻¹ extracted from the X/Y positions over time of a control cell (black columns) and a cell treated with donors as indicated in b and d. (d) Graphs represent X/Y positions of glioblastoma cells over time as indicated in b and c.