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. 2016 Feb 5;9:68. doi: 10.1186/s13104-016-1892-y

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© Sakurai et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Effect of IL-17A on MMP-3 production by HS-SY-II cells. a Representative the mRNA level of MMP-3 in HS-SY-II cells stimulated with IL-17A. Data are expressed as the mean ± SD of triplicate cultures. *Indicates statistical significance of p < 0.01. b Western blot for MMP-3 in HS-SY-II cells stimulated with IL-17A. c Represents immunofluorescent staining for IL-17R in HS-SY-II cells. Merge image is digital three-color overlay of IL-17R (green), rhodamine isothiocynate-phalloidin (red), and DAPI detection of nuclei (blue). The bars indicate 100 μm. d Representative the mRNA level of MMP-3 in HS-SY-II cells pretreated with IL-17R Ab, followed by incubation with IL-17A. Data are expressed as the mean ± SD of triplicate cultures. *Indicates statistical significance of p < 0.01