Fig. 2.

Deficiency of the urokinase-type plasminogen activator (uPA) accelerated the decrease of renal functions in a focal segmental glomerulosclerosis (FSGS) mouse model. a Proteinuria was expressed as total protein (mg/ml) over creatinine (mg/dl), and (b) plasma albumin was determined in wild-type (WT) and uPA^−/− groups during the course of the experiment until 4 weeks after Adriamycin treatment. ^# p < 0.05 vs. week 0 (W0); *p < 0.05 vs. the WT