Table 2.
Demographic and clinical characteristics of patients at the baseline, according to study site
| Patients at baseline n=837 | Sites in rural Laos | ||
|---|---|---|---|
| Salavan (n=223) |
Luang Namtha (n=379) |
Xieng Khouang (n=S235) |
|
| Demographic characteristics | |||
| Male, n(%) | 132 (59.2) | 196 (51.7) | 111 (47.2) |
| Age, median (IQR) | 9 (1-27) | 6 (1-23) | 7 (1-25) |
| BMI (Kg/m2), mean (SD) | 17.8 (3.88) | 17.3 (4.23) | 18.1 (4.16) |
| Pre-admission antibiotics consumption | 34 (15.3) | 118 (31.1) | 56 (23.8) |
| Current antibiotics prescription, n (%) | 98 (44.0) | 273 (72.0) | 121 (51.5) |
| -Penicillin M & V, n [%) | 6 (6.1) | 6 (2.2) | 27 (22.3) |
| -Penicillin A, n (%) | 31 (31.6) | 225 (82.4) | 19 (15.7) |
| -Cephalosporins, n (%) | 20 (20.4) | 13 (4.8) | 25 (20.7) |
| -Quinolones, n (%) | 24 (24.5) | 14 (5.1) | 8 (6.6) |
| -Macrolides, n (%) | 7 (7.1) | 11 (4.0) | 10 (8.3) |
| -Others® [%) | 10 (10.2) | 4 (1.5) | 32 (26.5) |
| Time (in days) between Onset of symptoms & Admission | 3 (2-4) | 3 (2-5) | 2 (1-4) |
| Clinical characteristics | |||
| Fever, n (%)* | 78 (35.0) | 97 (25.6) | 92 (39.2) |
| Neurological presentation, n (%)** | 105 (47.1) | 220 (58.2) | 180 (76.6) |
| Respiratory syndrome, n(%)*** | 183 (82.1) | 322 (85.2) | 177 (75.6) |
| Enteric syndrom, n (%)**** | 63 (28.3) | 174 (46.0) | 144 (61.3) |
| Undifferentiated fever, n (%)***** | 6 (8.2) | 4 (2.7) | 4 (4.9) |
* Fever defined by tympanic temperature >37.7°C
** Neurological syndrome includes the presence of at least one of these symptoms: stiffneck; cephalalgia; confusion
*** Respiratory syndrome includes the presence of at least one of these symptoms: lung crepitation; cough; dyspnoea
**** Enteric syndrom includes the presence of at least one of these symptoms: abdominal pain; vomiting; nausea; jaundice; diarrhoea
****** Undifferentiated fever includes the absence of any focal symptoms, coupled with the presence of at least one of these symptoms: fever; chills; rigors; myalgia