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a On H&E staining on gastrocnemius lateralis muscle of a 51-year-old male (FF3, IV-1) mild endomysial fibrosis as well as fiber size variation, internal nuclei, one atrophic rimmed vacuolated fiber (arrow in the middle) and small centrally located myofibrillar aggregates mainly in non-atrophic fibers (arrows in left corner) are evident. b. In modified trichrome staining of the same muscle the aggregates appear as darker stained areas
