Table 4.
Plasma fatty acid composition in control and TTP-treated micea
| Diet groups | ||||
|---|---|---|---|---|
| Fatty acid (wt %) | Control | 0.3 % TTP | 0.6 % TTP | 0.9 % TTP |
| Σ SFAs | 32.1 ± 1.5 | 31.8 ± 0.9 | 31.2 ± 0.6 | 30.9 ± 0.6 |
| Σ MUFAs | 22.7 ± 2.2 | 20.6 ± 3.1 | 23.8 ± 4.8 | 22.2 ± 2.4 |
| Σ n-6 PUFAs | 36.9 ± 1.1 | 37.8 ± 2.1 | 35.0 ± 3.9 | 36.7 ± 2.1 |
| C22:5n-6 | 0.29 ± 0.05 | 0.16 ± 0.04*** | 0.14 ± 0.06*** | 0.14 ± 0.04*** |
| Σ n-3 PUFAs | 7.8 ± 0.5 | 9.2 ± 0.8* | 8.9 ± 1.7 | 8.7 ± 0.4 |
| C20:5n-3 | 0.53 ± 0.07 | 0.62 ± 0.06 | 0.69 ± 0.22 | 0.70 ± 0.16 |
| C22:5n-3 | 0.24 ± 0.03 | 0.31 ± 0.04 | 0.32 ± 0.11 | 0.33 ± 0.09 |
| C22:6n-3 | 6.6 ± 0.5 | 7.7 ± 0.9 | 7.3 ± 1.4 | 7.2 ± 0.4 |
| Σ n-3 PUFA/Σ n-6 PUFA ratiob | 0.21 ± 0.02 | 0.24 ± 0.02* | 0.25 ± 0.03** | 0.24 ± 0.01* |
Abbreviations: SFAs saturated fatty acids; MUFAs monounsaturated fatty acids; PUFAs polyunsaturated fatty acids; TTP tetradecylthiopropionic acid
aMeans with standard deviation are shown (n = 7–8), and results were analyzed by one-way ANOVA with Dunnett’s post hoc test (P* < 0.05, P** < 0.01, P*** < 0.001)n-3
bPUFA/n-6 PUFA calculated as: (18:4n-3 + 18:3n-3 + 20:3n-3 + 20:4n-3 + 21:5n-3 + 22:6n-3 + 22:5n-3)/(18:3n-6 + 18:2n-6 + 20:4n-6 + 20:3n-6 + 20:2n-6 + 22:5n-6 + 22:4n-6 + 22:2n-6)