Table 3.
Outcomes of singleton pregnancies by NRTI backbone (n = 4762)
| ZDV + 3TC | FTC + TDF | ABC + 3TC | Other/Missing | P value | |
|---|---|---|---|---|---|
| Preterm, n (%) | |||||
| ᅟNo (≥37 wk) | 2762 (87.0) | 380 (86.2) | 249 (88.6) | 565 (84.0) | 0.13 |
| ᅟYes (<37 wk) | 412 (13.0) | 61 (13.8) | 32 (11.4) | 108 (16.0) | |
| Gestational age, n (%) | |||||
| ᅟ≥37 wk | 2762 (87.0) | 380 (86.2) | 249 (88.6) | 565 (84.0) | 0.31 |
| ᅟ32–36 wk | 317 (10.0) | 49 (11.1) | 24 (8.5) | 88 (13.1) | |
| ᅟ<32 wk | 95 (3.0) | 12 (2.7) | 8 (2.9) | 20 (3.0) | |
| Low birth weight, n (%) | |||||
| ᅟNo (≥2500 g) | 2604 (85.0) | 361 (85.1) | 235 (86.1) | 536 (84.5) | 0.95 |
| ᅟYes (<2500 g) | 460 (15.0) | 63 (14.9) | 38 (13.9) | 98 (15.5) | |
| Low birth weight in term infants, n (%) | |||||
| ᅟNo (≥2500 g) | 2492 (93.1) | 340 (92.6) | 226 (93.0) | 502 (93.0) | 0.99 |
| ᅟYes (<2500 g) | 184 (6.9) | 27 (7.4) | 17 (7.0) | 38 (7.0) | |
Abbreviations: NRTI nucleoside reverse transcriptase inhibitor, ZDV zidovudine, 3TC lamivudine, FTC emtricitabine, TDF tenofovir, ABC abacavir