Table 2.

Univariate analysis for acute bowel toxicity in patients receiving concurrent chemoradiation (n = 87)

Variables	Strata (n)	Grade ≥II, absent	Grade ≥II, present	p-value	Grade ≥III, absent	Grade ≥III, present	p-value
Age (years)	<48	15	30	0.81	32	13	0.09
	≥48	15	27		36	6
Type of hysterectomy	Wertheim's	9	21	0.52	23	7	0.80
	Simple	21	36		45	12
Type of RT	IMRT	18	31	0.75	41	8	0.07
	3D CRT	11	22		22	11
Concurrent chemotherapy	No	12	4	0.46	15	1	0.92
	Yes	72	15		81	6
Body mass index (kg m−2)	<25	19	29	0.26	40	8	0.19
	≥25	11	28		28	11
Abdominal surgery	Single	17	45	0.08	45	17	0.32
	Multiple	3	2		5	0
Co-morbidities	Yes	3	4	0.62	4	3	0.16
	No	27	53		64	16
Tobacco use	Yes	6	6	0.22	10	2	0.64
	No	24	51		58	17
V15 SB (cm3)	≥275	5	12	0.62	12	5	0.40
	<275	25	45		56	14
V30 SB (cm3)	≥190	6	14	0.63	15	5	0.69
	<190	24	43		53	14
V40 SB (cm3)	≥150	6	14	0.63	15	5	0.69
	<150	24	43		53	14
V15 LB (cm3)	≥250	2	10	0.16	9	3	0.77
	<250	28	47		59	16
V30 LB (cm3)	≥100	8	22	0.26	24	6	0.76
	<100	22	35		44	13
V40 LB (cm3)	≥90	6	18	0.25	18	6	0.66
	<90	24	39		50	13
V15 TB (cm3)	≥450	5	15	0.30	16	4	0.82
	<450	25	42		52	15
V30 TB (cm3)	≥330	3	12	0.19	13	2	0.38
	<330	27	45		55	17
V40 TB (cm3)	≥280	3	12	0.19	11	4	0.61
	<280	27	45		57	15
V15 PC (cm3)	≥1200	9	25	0.20	27	7	0.82
	<1200	21	32		41	12
V30 PC (cm3)	≥900	5	20	0.07	18	7	0.37
	<900	25	37		50	12
V40 PC (cm3)	≥750	4	15	0.16	14	5	0.59
	<750	26	42		54	14

3D CRT, three-dimensional conformal radiation; IMRT, intensity-modulated radiotherapy; LB, large bowel; PC, peritoneal cavity; RT, radiotherapy; SB, small bowel; TB, total bowel; V₁₅–V₄₀, volume of bowel getting the specified dose in gray.