Fig. 2.

(A) Plasma time curves of miR-29b and miR-1 (negative control) in healthy adults following consumption of 0.25 to 1 L milk (n = 5). (B) Abundance of miR-29b and miR-200c in peripheral blood mononuclear cells before (0 h) and after (6 h) consuming 1 L of milk (n = 5). (C) Treatment of human cells with 200 fmol/L miR-29b in milk exosomes decreases reporter gene activity (n = 2). (D) Plasma concentrations of miR-29b in mice fed an miRNA-normal (E+) vs. miRNA-depleted (E−) diet for 4 weeks (n = 5); *, p < 0.05. Reprinted with permission from Baier et al. (2014).