Table 1.
Differences in Patient Characteristics by HIV Serostatus
| Variables | HIV Positive n=26 |
HIV Negative n=164 |
p value |
|---|---|---|---|
| Gender | |||
| Male | 23 (89%) | 134 (82%) | 0.40 |
| Female | 3 (19) | 30 (18) | |
| Age (years) at diagnosis (mean) | 55.4 +/− 9.5 | 56.0 +/−7.6 | 0.73 |
| Body Mass Index at diagnosis (kg/m2) | 22.3 +/−4.8 | 26.1 +/−6.2 | 0.01 |
| Race/Ethnicity | |||
| White | 10 (39) | 34 (21) | 0.02 |
| Black | 14 (54) | 68 (42) | |
| Hispanic | 2 (8) | 52 (32) | |
| Asian | 0 | 10 (6) | |
| Insurance Status | |||
| Medicare | 11 (42) | 29 (18) | 0.01 |
| Medicaid | 1 (4) | 26 (16) | |
| Parkland health plus | 12 (46) | 69 (42) | |
| Private | 2 (8) | 12 (7) | |
| None | 0 (0) | 28 (17) | |
| Etiology of chronic liver disease | |||
| Hepatitis C Alone | 7 (26) | 32 (20) | <0.01 |
| Hepatitis B Alone | 8 (31) | 5 (3) | |
| Alcohol Alone | 1 (4) | 16 (10) | |
| Hepatitis C and Alcohol | 7 (27) | 92 (56) | |
| Hepatitis B and Alcohol | 3 (12) | 5 (3) | |
| Non-alcoholic steatohepatitis | 0 | 7 (4) | |
| Other/Unknown | 0 | 7 (4) | |
| Symptoms at diagnosis | |||
| Yes | 13 (50) | 98 (60) | 0.35 |
| ECOG functional status | |||
| 0–1 | 21 (81) | 138 (84) | 0.18 |
| ≥2 | 5 (19) | 26 (16) | |
| Total serum bilirubin (mg/dl) (median) | 0.9 (0.2–6.5) | 1.4 (0.2–37) | 0.01 |
| Serum albumin (g/dl) (median) | 3.4 (2.0–4.7) | 2.9 (1.3–4.6) | 0.03 |
| Serum platelets (k/ul) (median) | 137 (17–426) | 121 (6–569) | 0.41 |
| Serum AST (u/l) (median) | 139 (17–422) | 132 (6–1089) | 0.52 |
| Serum ALT (u/l) (median) | 46 (15–245) | 56 (11–601) | 0.51 |
| MELD (median) | 10 (6–43) | 10 (6–43) | 0.12 |
| Child-Pugh-Turcotte | |||
| A | 16 (62) | 52 (32) | 0.01 |
| B | 7 (27) | 67 (41) | |
| C | 3 (12) | 45 (27) | |
| HIV RNA (copies/ml) (median) | 400 (48–34,200) | ||
| CD 4+ cells (per mm3) (median) | 247 (17–813) | ||
| HAART therapy (Yes/No) | 19/26 | ||
| Visits within 2 years of HCC diagnosis | |||
| Primary care physician (median) | 6 (0–22) | 1 (0–39) | 0.02 |