TABLE IV.
Significant Features Utilizing Two Different Modalities
| fALFF data | |||||||||||
| BD vs. MDD (16 significant features) | BD vs. HC (5 significant features) | MDD vs. HC (28 significant features) | |||||||||
| AAL No. | Brain area | Weight | AAL No. | Brain area | Weight | AAL No. | Brain area | Weight | |||
| ● | 116 | Vermis_10 | 1.5199 | ● | 65 | Angular_L | −2.5417 | ● | 114 | Vermis_8 | −1.186 |
| ● | 75 | Pallidum_L | −1.2746 | 102 | Cerebelum_7b_R | 1.7775 | ● | 10 | Frontal_Mid_Orb_R | −0.889 | |
| 30 | Insula_R | 1.2559 | 5 | Frontal_Sup_Orb_L | 1.6366 | ● | 70 | Paracentral_Lobule_R | 0.8612 | ||
| ● | 109 | Vermis_1_2 | −1.2051 | 13 | Frontal_Inf_Tri_L | 1.1592 | ● | 82 | Temporal_Sup_R | −0.8009 | |
| ● | 65 | Angular_L | −1.1779 | 48 | Lingual_R | −0.9787 | 52 | Occipital_Mid_R | 0.7818 | ||
| 15 | Frontal_Inf_Orb_L | 1.0519 | 96 | Cerebelum_3_R | 0.761 | ||||||
| 70 | Paracentral_Lobule_R | −0.9367 | ● | 94 | Cerebelum_Crus2_R | 0.673 | |||||
| 54 | Occipital_Inf_R | −0.8713 | ● | 22 | Olfactory_R | 0.6635 | |||||
| 69 | Paracentral_Lobule_L | −0.7827 | 27 | Rectus_L | 0.6544 | ||||||
| 76 | Pallidum_R | −0.7475 | 91 | Cerebelum_Crus1_L | 0.6384 | ||||||
| 82 | Temporal_Sup_R | 0.5871 | 107 | Cerebelum_10_L | 0.6229 | ||||||
| 1 | Precentral_L | −0.568 | 11 | Frontal_Inf_Oper_L | 0.6149 | ||||||
| 103 | Cerebelum_8_L | −0.4937 | 66 | Angular_R | 0.611 | ||||||
| 80 | Heschl_R | 0.4182 | 18 | Rolandic_Oper_R | −0.6016 | ||||||
| 18 | Rolandic_Oper_R | 0.3262 | 116 | Vermis_10 | −0.5491 | ||||||
| 108 | Cerebelum_10_R | −0.2163 | 79 | Heschl_L | 0.5066 | ||||||
| 102 | Cerebelum_7b_R | 0.4695 | |||||||||
| 59 | Parietal_Sup_L | −0.4365 | |||||||||
| 58 | Postcentral_R | −0.3897 | |||||||||
| 71 | Caudate_L | 0.3272 | |||||||||
| 5 | Frontal_Sup_Orb_L | 0.2623 | |||||||||
| 26 | Frontal_Mid_Orb_R | 0.2181 | |||||||||
| 109 | Vermis_1_2 | 0.2091 | |||||||||
| 92 | Cerebelum_Crus1_R | 0.1977 | |||||||||
| 43 | Calcarine_L | −0.1931 | |||||||||
| 42 | Amygdala_R | −0.1826 | |||||||||
| 33 | Cingulum_Mid_L | 0.1711 | |||||||||
| 51 | Occipital_Mid_L | 0.17 | |||||||||
| VBM-GM data | |||||||||||
| BD vs. MDD (6 significant features) | BD vs. HC (16 significant features) | MDD vs. HC (6 significant features) | |||||||||
| AAL No. | Area name | Weight | AAL No. | Area name | Weight | AAL No. | Area name | Weight | |||
| ● | 14 | Frontal_Inf_Tri_R | 6.2067 | 92 | Cerebelum_Crus1_R | 11.7555 | ● | 13 | Frontal_Inf_Tri_L | 4.8525 | |
| 46 | Cuneus_R | −4.2253 | ● | 12 | Frontal_Inf_Oper_R | 9.7199 | 9 | Frontal_Mid_Orb_L | 1.9852 | ||
| ● | 12 | Frontal_Inf_Oper_R | 3.617 | 32 | Cingulum_Ant_R | 9.236 | 41 | Amygdala_L | 1.8239 | ||
| 13 | Frontal_Inf_Tri_L | 2.6796 | 56 | Fusiform_R | −7.9112 | 104 | Cerebelum_8_R | −1.3948 | |||
| ● | 31 | Cingulum_Ant_L | 2.6275 | 91 | Cerebelum_Crus1_L | 7.6179 | 73 | Putamen_L | 1.3436 | ||
| 56 | Fusiform_R | −0.6357 | 64 | SupraMarginal_R | 7.2463 | 13 | Frontal_Inf_Tri_L | 0.9092 | |||
| 52 | Occipital_Mid_R | −5.7348 | |||||||||
| 106 | Cerebelum_9_R | 5.3595 | |||||||||
| ● | 29 | Insula_L | 3.7479 | ||||||||
| 9 | Frontal_Mid_Orb_L | −3.2096 | |||||||||
| 31 | Cingulum_Ant_L | 2.921 | |||||||||
| ● | 114 | Vermis_8 | −2.9008 | ||||||||
| 89 | Temporal_Inf_L | −2.6185 | |||||||||
| 98 | Cerebelum_4_5_R | −2.2865 | |||||||||
| 115 | Vermis_9 | −2.0829 | |||||||||
| 46 | Cuneus_R | −1.7973 | |||||||||
“AAL No.” stands for the area order of the AAL templates a feature corresponds to, while “Area name” is the abbreviated name of the brain region related to that specific number.
The weights of the significant features dedicated to 6 classification conditions are listed in the “Weight” columns. Denoted with black dots, all the consensus features are included by the significant features.