Figure 2.
Change Δ (treatment effect) between pre-treatment and 12 weeks post-treatment for plasma levels of n-terminal pro-brain natriuretic peptide (nt-pro BNP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), c-reactive protein (CRP) and reactive oxygen species (ROS). Probability values are comparisons between heart failure control dogs (HF-CON) and elamipretide-treated heart failure dogs (HF+ELA). Statistical significance based on t-statistic for two means. All bar graphs are depicted as Mean±SEM.