Figure 1.
Severity of the Rh1G69D retinal phenotype depends on genetic background. (A) The eye sizes for 173 DGRP/Donor F1 crosses. There is a very strong strain effect on the severity of the retinal degeneration as measured by eye size (P < 2.2 × 10−16). Median ± SD. (B) Examples of the qualitative differences in eye phenotype across the size spectrum shown in (A). Small = three strains with the smallest eyes. Medium = strains with eye size from the middle of the distribution. Large = three strains with the largest eyes. RAL# = the strain number of the DGRP strain.