Table 1.
Top candidate genes
| Rank order | Candidate gene | SNPa | P-valuea | Human orthologs | OMIM | Retinal diseaseb |
|---|---|---|---|---|---|---|
| 1 | CG2004 | X:8608255 | 2.08E−08 | Many | — | — |
| 2 | Cdk5 | 2R:11457488 | 3.97E−07 | CDK5 | 616 342 | Yes |
| 3 | CG15666 | 2R:17230301 | 1.47E−06 | BBS9 | 615 986 | Yes |
| 4 | CG31468 | 3R:19525550 | 2.10E−06 | ODF3/3B | No | No |
| 5 | CG1785 | X:8609333 | 2.86E−06 | GLTSCR2 | No | No |
| 6 | Adgf-D | 3R:9530149 | 3.79E−06 | CECR1 | 615 688 | Yes |
| 7 | fred | 2L:3942577 | 5.05E−06 | KIRREL/2/3 | 612 581 | No |
| 8 | prosap | 2R:10004495 | 5.14E−06 | SHANK1/2/3 | 613 436 | Yes |
| 9 | CG16885 | 2L:13933849 | 6.28E−06 | ZNF512,ZNF512B,TPRX1 | No | No |
| 10 | Hexo2 | X:8605385 | 6.75E−06 | HEXA/B | 272 800 | Yes |
| 11 | hppy | 2R:15095769 | 8.12E−06 | MAP4K1/2/3/5 | No | Yes |
| 12 | lola | 2R:6387329 | 8.47E−06 | None | — | — |
| 13 | Pde1c | 2L:11820427 | 8.96E−06 | PDE1A/B/C | No | No |
| 14 | CG43795 | 2R:19369219 | 9.73E−06 | GPR179, GPR158 | 614 565 | Yes |
aMost significant associated SNP in the candidate gene and the associated P-value.
bBased on PubMed search.