Fig 1. Expression of mitotic kinesins, including KIF11, is upregulated in GBM.
(A) Differential expression analysis by RNA-Seq from radiographically-localized biopsies of non-enhancing (NE) and contrast-enhancing (CE) regions of human GBM surgical specimens (B) Correlation of cell type-specific marker genes with KIF11 expression (C) qPCR was performed for the listed mitotic regulators on RNA isolated from TICs and matched non-TICs from three patient derived xenografts.
