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Endocannabinoid levels in striatal slices. (A) Levels of 2-AG and AEA in striatal tissue slices of wild-type and DAGLα-KO mice incubated in aCSF (n = 6–8, 4 h). (B and C) Levels of (B) 2-AG and (C) AEA following incubation of rat striatal tissue slices with vehicle, 1 µM KML29, 1 µM KML29 + 1 µM KT172, or 1 µM KML29 + µM KT185 (n = 5–6, 4 h). Experiments were carried out as described in Experimental Procedures. Data are presented as mean ± SE. *P < 0.05, **P < 0.01.
