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. 2015 Dec 28;113(4):1056–1061. doi: 10.1073/pnas.1523303113

Fig. S4.

Fig. S4.

Fusion peptide cleavage site of PIV5 and HeV F. (A) Catalytic site of furin in complex with the inhibitor m-guanidinomethyl-phenylacetyl-Arg-Val-Arg-(amidomethyl)-benzamidine (m-guanidinomethyl-Phac-RVR-Amba) (PDB ID code 4OMC). (B) Structural alignment of cathepsin L in complex with a natural peptide substrate, histone H3 (PDB ID code 3K24) and the inhibitor AZ12878478 (PDB ID code 3HHA). (C) Structural alignment of cathepsin L in complex with the natural polypeptide inhibitors chagasin (PDB ID code 2NQD) and MHC class II Ii p41 variant (PDB ID code 1ICF).