Fig 2. Syn-3 preferentially binds Cav2.3 while Syn-1A preferentially binds Cav1.3.
Representative blots show HEK293 cells co-transfected with Cav1.3 (A) or Cav2.3 (C) with either Syn-1A or Syn-3, then subjected to co-IP with anti-Syn-1A or Syn-3 antibody. Co-precipitated proteins were identified with the indicated antibodies. Densitometric analysis of the co-precipitated Cav1.3 (B) or Cav2.3 (D), expressed as percent recovery of total lysate inputs. Values are means±SEM, n = 3; *p<0.05, **p<0.01.