Table 1.

Prebiotic Supplementation and Cardiometabolic Health: Participant Eligibility Criteria

Inclusion Criteria: Population: Men and women 40–75 years of age Sedentary to Recreationally Active (i.e., self-reported physical activity < 150 minutes/week) BMI: 25–40 kg/m2 Prediabetic or at increased risk: ADA Screener (score ≥ 5), HbA1c (5.7–6.4 mg/dl), FBG (100–125 mg/dl) or OGTT (140–200 mg/dl) Doctor’s Note for patients with CHD Blood pressure: ≤ 160/100 mm/Hg Total Cholesterol and Triglycerides: ≤ 300 mg/dl and ≤ 450 mg/dl Exclusion Criteria: Current smokers Diabetic or use of diabetes medications (i.e., metformin or insulin) Health history of: respiratory disease, unstable CHD (i.e., chest pain or heart failure), inflammatory bowel disease, cancer, neurological or hematological disorders, or substance abuse Antibiotic use in the past 3 months Current enrollment in other research studies Currently pregnant or intent to become pregnant Currently taking prescribed NSAIDs, antioxidants, or fiber supplements Recent surgery Food allergies, intolerances, and/or religious, cultural, or other dietary restrictions

Note: BMI=body mass index; ADA=American Diabetes Association; FBG=fasting blood glucose; OGT=oral glucose tolerance; CHD=coronary heart disease; NSAID= non-steroidal anti-inflammatory drugs