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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Cancer Immunol Res. 2015 Nov 6;3(12):1308–1315. doi: 10.1158/2326-6066.CIR-15-0116

Figure 1.

Figure 1

Domain specificity of PD-L1 mAbs. 9A11, E1L3N, and SP142 recognize an epitope in the cytoplasmic domain of PD-L1 while most other mAbs used for therapeutics, flow cytometry and IHC, recognize an epitope in the extracellular domain of PD-L1, including 2A3, 5A4, 7G11, and 015.