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. 2016 Feb 5;11(2):e0148645. doi: 10.1371/journal.pone.0148645

Fig 6. Effect of EGCG on IL-1β induced-degradation of IκBα and -phosphorylation of p38 and ERK in orbital fibroblasts.

Fig 6

Orbital fibroblasts were pre-treated with EGCG (100 μM) for 1 hour, followed by treatment with IL-1β (10 ng/mL) for 10 minutes. The degradation of IκBα and the phosphorylation of p38 and ERK were confirmed by Western blot analysis. Similar results were observed in three independent experiments with orbital fibroblasts of passages (P)7 and P10 from TAO patient #53. P, number of passages.