. 2016 Feb 5;11(2):e0148571. doi: 10.1371/journal.pone.0148571

Table 7. Additive and Dominance Effects for Chromosome 4 QTL in C.B.4.2 Mice.

C.B. 4.2
	MALES
	C3H/C3H (10)	C3H/B10 (17)	B10/B10 (9)	additive effect	dominance effect
Outer minor axis (mm)^A^,^C	1.13 ± 0.02	1.14 ± 0.01	1.16 ± 0.02	0.02	-0.01
CSA (mm²)^A^,^C	1.08 ± 0.04	1.08 ± 0.02	1.14 ± 0.02	0.03	-0.03
total displacement (mm)^A	0.54 ± 0.08	0.66 ± 0.05	0.49 ± 0.06	-0.03	0.15
post-yield displacement (mm)^A	0.42 ± 0.08	0.53 ± 0.05	0.43 ± 0.05	0.01	0.11
stiffness (N/mm)^A	134 ± 9	123 ± 5	108 ± 6	-13.15	2.47
yield Load (N)^A	14.9 ± 0.5	14.3 ± 0.4	12.8 ± 0.6	-1.07	0.43
max load (N)^A	19.6 ± 1.0	19.5 ± 0.4	17.3 ± 0.8	-1.13	1.11
	FEMALES
	C3H/C3H (4)	C3H/B10 (8)	B10/B10 (6)	additive effect	dominance effect
Outer minor axis (mm)^A^,^C	1.14 ± 0.01	1.16 ± 0.02	1.08 ± 0.03	-0.03	0.05
CSA (mm²)^A^,^C	1.05 ± 0.03	1.07 ± 0.03	0.95 ± 0.05	-0.05	0.07
total displacement (mm)^A	0.62 ± 0.09	0.88 ± 0.15	0.63 ± 0.10	0.01	0.26
post-yield displacement (mm)^A	0.50 ± 0.09	0.77 ± 0.12	0.48 ± 0.10	-0.01	0.28
stiffness (N/mm)^A	116 ± 6	125 ± 5	105 ± 10	-5.90	14.55
yield Load (N)^A	13.9 ± 1.9	15.0 ± 0.5	12.7 ± 0.9	-0.62	1.70
max load (N)^A	19.4 ± 1.2	19.8 ± 0.43	17.8 ± 1.0	-0.82	1.19
	MALES AND FEMALES AVERAGE
	C3H/C3H (14)	C3H/B10 (25)	B10/B10 (15)	additive effect	dominance effect
Outer minor axis (mm)^A^,^C	1.14	1.15	1.12	-0.01	0.02
CSA (mm²)^A^,^C	1.07	1.08	1.05	-0.01	0.02
total displacement (mm)^A	0.58	0.77	0.56	-0.01	0.20
post-yield displacement (mm)^A	0.46	0.65	0.46	-0.00	0.19
stiffness (N/mm)^A	125	124	106	-9.52	8.51
yield Load (N)^A	14.4	14.6	12.7	-0.84	1.06
max load (N)^A	19.5	19.7	17.5	-0.97	1.15

Values are means ± SE; N, numbers of mice.

^A genotype effect

^C sex by genotype interaction

Additive effect = ½ [average phenotype (C3H/C3H)–average phenotype (B10/B10)]

Dominance effect = average phenotype (C3H/B10)– ½ [average phenotype (C3H/C3H) + average phenotype (B10/B10)]