Fig 4. HDACs Rpd3 and Hos2 promote Cmr1 binding in the ARG1 coding regions.

A) Cmr1 occupancy in the WT and histone methyltransferase mutants (set1Δ and set2Δ) at ARG1 5’ and 3’ ORFs is shown. B) Occupancy of Cmr1 at the induced ARG1 gene in WT, gcn4Δ and histone acetyltransferase mutant (gcn5Δ/esa1ts) is shown. C-D) Cmr1 ChIP occupancies in the induced WT and in histone deacetylase (HDACs) mutants (hos2Δ, rpd3Δ, and hos2Δ/rpd3Δ) at the ORFs of ARG1 (C) and HIS4 (D) are shown.