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. 2016 Feb 5;11(2):e0147744. doi: 10.1371/journal.pone.0147744

Table 3. Results of meta-analysis of the studies on comparison between CB-DOT and Family-based DOT, Workplace-based DOT and administered treatment in TB control.

Styles of Meta No. Of studies No. of participants Variance between studies Pooled RR (95% CI)
Q(p) I2 (%)
1. Comparison between CB-DOT and Family-based DOT
Successful treatment
All studies on all PTB 4 2880 0.21 33 0.99 [0.95, 1.04]
All cases(RCT) 3 2619 0.17 43 0.99 [0.94,1.03]
Cured treatment
All studies on all PTB 3 1233 0.39 0 1.09 [0.99,1,09]
All cases(RCT)  2 972 0.23 31 1.08 [0.97,1.20]
Completed treatment
All studies on all PTB 3 1233 0.55 0 0.93 [0.75,1.15]
All cases(RCT) 2 972 0.62 0 0.97 [0.791.20,]
Death
All studies on all PTB 3 1973 0.87 0 0.81 [0.63,1.04]
All cases(RCT) 2 1712 0.61 0 0.81 [0.63,1.05]
Failure
All studies on all PTB 3 1772 0.89 0 0.67 [0.13,3.47]
All cases(RCT) 2 1712 0.9 0 0.88 [0.12,6.40]
2. Comparison of Successful treatment between CB-DOT DOT and Workplace-based DOT
All PTB 2 1330 0.19 43 0.85 [0.79, 0.90]
New PTB 2 1240 0.2 39 0.84 [0.79, 0.90]
3. Comparison between CB-DOT and Self-administered treatment based on all studies on all PTB)
Successful treatment 3 534 0.69 0 1.13 [1.03, 1.24]
Cured treatment 2 225 0.46 0 1.24 [1.04, 1.48]
Completed treatment 2 225 0.36 0 0.72 [0.32, 1.60]
Death 2 225 0.65 0 1.02 [0.29, 3.60]
Failed treatment 2 225 0.95 0 1.19 [0.26, 5.50]