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. 2016 Feb 5;11(2):e0148206. doi: 10.1371/journal.pone.0148206

Table 3. Hematological Variables.

Variable No Acetazolamide Acetazolamide F-score p-value
No AMS AMS No AMS AMS
WBC (109/L) 6.0 ± 1.6 5.9 ± 1.7 6.0 ± 1.6 5.9 ± 1.8 0.08 0.97
RBC (109/L) 5.0 ± 0.4* 4.8 ± 0.4* 4.9 ± 0.5 4.9 ± 0.4 2.79 0.04
Hemoglobin (g/dL) 15.4 ± 1.2 15.0 ± 1.0 15.2 ± 1.3 15.3 ± 1.4 1.52 0.21
Hematocrit (%) 45.5 ± 3.4 44.4 ± 3.0 45.2 ± 3.8 45.5 ± 3.8 1.28 0.28
Platelet (109/L) 226. 8 ± 46.1* 253.4 ± 54.5* 241.9 ± 52.6 249.6 ± 67.9 3.13 0.03
MCV (μg/cell) 91.8 ± 4.1 93.5 ± 3.8 93.2 ± 5.1 92.3 ± 5.4 1.84 0.14
MCH (μg/cell) 31.0 ± 1.3 31.5 ± 0.9 31.5 ± 1.2 30.9 ± 1.6 2.76 0.04
MCHC (μg/cell) 33.8 ± 0.8 33.7 ± 0.9 33.6 ± 1.1 33.5 ± 1.1 0.93 0.43
RDW (%) 13.7 ± 1.0* 13.3 ± 0.8Ω 13.6 ± 0.9 14.2 ± 1.5*Ω 6.25 <0.01
Eosinophils (109/L) 2.2 ± 1.8 2.5 ± 1.9 2.3 ± 1.9 2.4 ± 2.3 0.22 0.89
Estimated Change in Plasma Volume (%) -7.2 ± 11.1 -7.5 ± 11.9 -4.6 ± 13.2 -6.1 ± 13.3 0.51 0.67
Iron (μg/dL) 112.5 ± 38.8 127.3 ± 51.8 122.4 ± 41.2 109.5 ± 45.9 1.93 0.13
Iron Saturation (%) 35.9 ± 14.0 39.6 ± 14.9 39.8 ±15.8 34.6 ± 15.7 1.57 0.20
TIBC (μg/dL) 323.0 ± 45.1 321.6 ± 40.6 316.9 ± 52.4 326.6 ± 49.1 0.34 0.79
UIBC (μg/dL) 210.2 ± 59.4 195.9 ± 55.3 195.3 ± 65.5 216.0 ± 76.2 1.23 0.30

*, Ω—indicates significant differences, p<0.05; Degrees of freedom = 3