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. Author manuscript; available in PMC: 2016 Feb 5.
Published in final edited form as: Stat Med. 2014 Oct 2;33(29):5111–5125. doi: 10.1002/sim.6313

Table 2.

NSABP B-14 data analysis based on various restricted models

Local occurrence
Distant occurrence
Mean SD 2.5% 97.5% Mean SD 2.5% 97.5%
Random intercept Cox restricted model
Regression coefficients
Age −0.04 0.008 −0.056 −0.024 −0.026 0.007 −0.039 −0.012
Treat −1.274 0.183 −1.642 −0.938 −0.713 0.145 −1.019 −0.443
Tumor size 0.037 0.007 0.025 0.051 0.042 0.006 0.03 0.053
Variance of random effect
Intercept 4.36 0.676 3.223 5.887
Multivariate random effects Cox restricted model
Regression coefficients
Age −0.036 0.013 −0.061 −0.01 −0.02 0.013 −0.046 0.005
Treat −1.425 0.214 −1.874 −1.023 −0.843 0.175 −1.175 −0.504
Tumor size 0.041 0.011 0.021 0.063 0.043 0.01 0.024 0.062
Variances of random effects
Intercept 4.264 0.813 2.676 5.899
Age 0.024 0.003 0.018 0.032
Tumor size 0.018 0.003 0.014 0.024