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. Author manuscript; available in PMC: 2016 Feb 5.
Published in final edited form as: Stat Med. 2014 Oct 2;33(29):5111–5125. doi: 10.1002/sim.6313

Table 3.

NSABP B-14 data analysis based on various general models

Distant Recurrence
Local Recurrence
Without local recurrence
After local recurrence
Mean SD 2.5% 97.5% Mean SD 2.5% 97.5% Mean SD 2.5% 97.5%
Random intercept Cox general model
Regression coefficients
Age −0.035 0.008 −0.051 −0.018 −0.022 0.007 −0.037 −0.010 −0.007 0.015 −0.036 0.023
Treat −1.130 0.181 −1.512 −0.802 −0.616 0.153 −0.949 −0.340 0.051 0.332 −0.571 0.705
Tumor size 0.03 0.008 0.017 0.046 0.035 0.007 0.024 0.049 0.028 0.013 0.004 0.055
Variance of random effect
Intercept 2.617 1.143 1.025 5.353
Multivariate random effects Cox general model
Regression coefficients
Age −0.043 0.017 −0.077 −0.012 −0.029 0.016 −0.063 0.001 −0.005 0.023 −0.050 0.041
    Treat −1.723 0.252 −2.242 −1.236 −1.190 0.223 −1.648 −0.766 −0.563 0.416 −1.370 0.215
    Tumor size 0.052 0.014 0.025 0.079 0.055 0.014 0.028 0.083 0.05 0.019 0.010 0.087
Variances of random effects
    Intercept 8.733 1.693 5.753 12.619
    Age 0.032 0.006 0.022 0.044
    Tumor size 0.023 0.004 0.017 0.031