BALB/c and BL6 mice were subjected to subacute femoral artery occlusion
via the placement of a single AC on the proximal femoral artery (1AC) for
15-days. A. Representative H&E sections demonstrating TA
morphology after 15 days of 1AC subacute ischemia; R, right (non-surgical limb;
black bar); L, left (surgical limb; grey bar). B, Percentage TA
myofibers with centralized nuclei. C, Percentage TA noncontractile
tissue (NCT). Values are presented as means ± SEM. *
P<0.05 v strain specific contralateral (R) control.
D, Myofiber cross-sectional area (CSA) in BALB/c and BL6 TA.
Mean CSA are presented as means ± SEM % change from
contralateral (R) control. *P<0.05 vs. BL6.
Distribution of skeletal muscle myofiber size was calculated in (E)
BALB/c and (F) BL6 TA muscles. Values are presented as means
± SEM. *P<0.05 v strain specific contralateral
(R) control.