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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Vasc Surg. 2015 Aug 5;64(4):1101–1111.e2. doi: 10.1016/j.jvs.2015.06.139

Figure 5. Genetic divergence of ischemic skeletal muscle myofiber morphology after 1AC-mediated subacute ischemia.

Figure 5

BALB/c and BL6 mice were subjected to subacute femoral artery occlusion via the placement of a single AC on the proximal femoral artery (1AC) for 15-days. A. Representative H&E sections demonstrating TA morphology after 15 days of 1AC subacute ischemia; R, right (non-surgical limb; black bar); L, left (surgical limb; grey bar). B, Percentage TA myofibers with centralized nuclei. C, Percentage TA noncontractile tissue (NCT). Values are presented as means ± SEM. * P<0.05 v strain specific contralateral (R) control. D, Myofiber cross-sectional area (CSA) in BALB/c and BL6 TA. Mean CSA are presented as means ± SEM % change from contralateral (R) control. *P<0.05 vs. BL6. Distribution of skeletal muscle myofiber size was calculated in (E) BALB/c and (F) BL6 TA muscles. Values are presented as means ± SEM. *P<0.05 v strain specific contralateral (R) control.