Identified and validated analytes by Myriad-RBM (MR). In comparison to control samples, BDNF, NrCAM, Clusterin, Adiponectin, ApoE, VCAM-1, and Myoglobin were significantly elevated in JNCL samples. Bars indicate mean ± SEM. Statistical significance determined using Student’s t test for all analytes except NrCAM, determined by Mann-Whitney U test (***, P < 0.0001; *, 0.002 ≤ P ≤ 0.05).