Table 3.
Lipid | Na | [mβCD] (mM)b | c | ks × 103 (s−1)d | kf × 103 (s−1)e |
---|---|---|---|---|---|
DMPC | 82 | 2.5 | 0.391 ± 0.002 | 2.38 ± 0.03 | 57.4 ± 1.2 |
SOPC | 95 | 2.5 | 0.312 ± 0.004 | 8.2 ± 0.2 | 138.2 ± 3.9 |
DOPC | 49 | 1.0 | 0.226 ± 0.004 | 0.98 ± 0.10 | 36.7 ± 0.8 |
The method of generating uncertainties in the fitting parameters is described in the Curve Fitting subsection.
The number of replicate bilayers measured.
The concentration of mβCD used (see the Materials and Methods).
Fitting parameter corresponding to the initial mole fraction of the slow population of cholesterol.
Fitting parameter corresponding to the rate constant for the depletion of the slow population of cholesterol.
Fitting parameter corresponding to the rate constant for the depletion of the fast population of cholesterol.