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. 2016 Feb 2;110(3):635–645. doi: 10.1016/j.bpj.2015.11.021

Table 3.

Experimental Parameters and Fitting Results for the Two-Population Model of Cholesterol

Lipid Na [mβCD] (mM)b χs0c ks × 103 (s−1)d kf × 103 (s−1)e
DMPC 82 2.5 0.391 ± 0.002 2.38 ± 0.03 57.4 ± 1.2
SOPC 95 2.5 0.312 ± 0.004 8.2 ± 0.2 138.2 ± 3.9
DOPC 49 1.0 0.226 ± 0.004 0.98 ± 0.10 36.7 ± 0.8

The method of generating uncertainties in the fitting parameters is described in the Curve Fitting subsection.

a

The number of replicate bilayers measured.

b

The concentration of mβCD used (see the Materials and Methods).

c

Fitting parameter corresponding to the initial mole fraction of the slow population of cholesterol.

d

Fitting parameter corresponding to the rate constant for the depletion of the slow population of cholesterol.

e

Fitting parameter corresponding to the rate constant for the depletion of the fast population of cholesterol.