Table 4.
Summary of Models of Cholesterol-Phospholipid Interactions in Lipid Membranes
| Model | Number of Characteristic χCa (0.66 > χC > 0.30) | Dependent on PC-Lipid Head or Tail?b |
|---|---|---|
| Umbrella (at solubility limit) | 0 | head |
| Condensed-complex | 1 | tail |
| Cholesterol bilayer domain | 1 | both |
| Umbrella (regular distributions) | ≥3 | head |
| Superlattice | ≥3 | head |
a
The number of characteristic χC at which the accessibility of cholesterol is predicted to change sharply.
b
Statement of whether the predictions of the model vary with the structure of the phospholipid head, tail, or both.