Figure 1.

Schematic of the DOM. I, current; J, flux; GK, glucokinase; PFK, phosphofructokinase; PDH, pyruvate dehydrogenase; ANT, adenine nucleotide translocator; ER, endoplasmic reticulum; hyd, hydrolysis; PMCA, plasma membrane Ca²⁺ ATPase. The modification to the model considered in this report is symbolized by the activating arrow from Ca²⁺ to $J_{\text{PDH}}.$ To see this figure in color, go online.