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Collagen fibers straightening. (a) The fractal analysis from Chow et al. (3) and the normalized intensity measurement both show delayed collagen fiber realignment (n = 6). (b) The ratio between SHG and TPEF intensity in collagen fiber bundles stained with fluorescein was evaluated at strains of 0 and 40%. Mann-Whitney U-test with ∗∗∗.
