Table 6. Concentration of amino acids (μMol/l) at baseline and at the end of intervention.
| Amino acids |
Group A (n=3) |
Group B (n=4) |
Group C (n=6) |
Pre to post supplementation difference across groups (ANOVA) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Week 12 | Mean difference | Baseline | Week 12 | Mean difference | Baseline | Week 12 | Mean difference | P | |
| Leucine | 147.3±8.1 | 175.3±24.6 | 28.0±29.1 | 224.0±82.5 | 187.0±21.5 | −37.0±75.3 | 142.5±36.4 | 145.8±23.0 | 3.3±33.3 | 0.250 |
| Isoleucine | 64.7±7.6 | 78.7±6.0 | 14.0±14.0 | 101.7±24.0a,b | 65.3±9.6c | −36.5±15.4 | 61.7±10.8 | 66.2±11.4 | 4.5±14.7 | 0.002 |
| Valine | 192.0±23.6 | 219.7±43.7 | 27.7±46.1 | 259.5±41.5a | 203.8±39.7c | −55.8±27.6 | 175.8±42.1 | 198.5±37.0 | 22.7±39.3 | 0.017 |
| Alanine | 223.0±93.2 | 250.7±84.8 | 27.7±84.2 | 254.5±47.7 | 212.3±54.4c | −42.3±23.0 | 241.3±46.1 | 259.7±39.1 | 18.3±33.8 | 0.119 |
| Glycine | 180.0±51.6 | 172.7±110.0 | −7.3±59.1 | 186.0±31.4 | 156.3±17.9c | −29.8±18.5 | 193.2±73.1 | 223.5±96.7c | 30.3±28.1 | 0.059 |
| Proline | 141.0±33.9 | 140.3±5.8 | −0.7±39.0 | 132.5±12.7 | 114.8±22.9 | −17.8±26.0 | 112.5±26.8 | 128.0±40.0 | 15.5±32.2 | 0.310 |
All values are means±standard deviation.
Abbreviations: ANOVA, analysis of variance; A, standard essential amino-acid mixture (EAAs); B, EAAs containing 40% leucine; C, placebo.
a
Denotes significantly different from placebo (P<0.05).
b
Denotes significantly different from group A (P<0.05)
c
Denotes significantly different from baseline value (P<0.05).