Table-II.
Association between combinations of NFKB1 -94 ins/del ATTG polymorphism and NFKBIA -826C>T polymorphism and lung cancer risk.
| Genotype | Case | Control | OR (95% CI) | P | |
|---|---|---|---|---|---|
| -94 ins/del ATTG | -826C>T | ||||
| Ins/ins | CC | 259 (36.1%) | 232 (32.3%) | 1.000 | -- |
| Ins/del | CC | 134 (18.7%) | 179 (24.9%) | 0.671 (0.504-0.892) | 0.006* |
| Del/del | CC | 20 (2.8%) | 50 (7.0%) | 0.358 (0.207-0.620) | <0.001* |
| Ins/ins | CT | 144 (20.1%) | 103 (14.3%) | 1.252 (0.920-1.705) | 0.153 |
| Ins/del | CT | 99 (13.8%) | 95 (13.2%) | 0.934 (0.669-1.302) | 0.685 |
| Del/del | CT | 8 (1.1%) | 25 (3.5%) | 0.287 (0.127-0.648) | 0.003* |
| Ins/ins | TT | 31 (4.3%) | 17 (2.4%) | 1.633 (0.881-3.029) | 0.119 |
| Ins/del | TT | 19 (2.6%) | 16 (2.2%) | 1.064 (0.535-2.117) | 0.860 |
| Del/del | TT | 4 (0.6%) | 1 (0.1%) | 3.583 (0.398-32.288) | 0.255 |
*
significant.